Genetics and Health

Junk DNA Affects Social Behavior

by Hsien Hsien Lei, PhD on June 15th, 2005

Do you consider yourself a social creature? Then maybe the microsatellite DNA associated with your vasopressin receptor gene is longer than average. (EurekAlert, June 9, 2005)

Unlike DNA which make-up the genes we usually talk about, microsatellite DNA is considered “junk DNA” because it isn’t a part of any gene and thus doesn’t code for protein. In male prairie voles, microsatellite DNA associated with the vasopressin receptor gene appears to affect social behavior. This finding supports results from previous studies which showed that the vasopressin receptor gene regulates social behaviors in many species.

In the prairie voles, males with long microsatellites had higher levels of vasopressin receptors in brain areas involved in social behavior and parental care, particularly the olfactory bulb and lateral septum. These males spent more time investigating social odors and approached strangers more quickly. They also were more likely to form bonds with mates, and they spent more time nurturing their offspring.

The researchers’ finding also has set a clear course for the next step. They want to build upon previous studies that identified a microsatellite sequence in the human vasopressin receptor that varies in length. “The variability in the microsatellite could account for some of the diversity in human social personality traits,” explains Hammock. “For example, it may help explain why some people are naturally gregarious while others are shy.” In particular, Young wants his research team to expound upon studies that have identified a link with autism.

More than 95% of DNA is considered “junk DNA” with unknown function. As this research and others are proving, junk DNA may not be as useless as previously thought.

Pointer from FuturePundit.

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