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Genetics and Health

Microcephalin and ASPM Genes Determine Human Brain Size

by Hsien Hsien Lei, PhD on September 9th, 2005

In the last 60,000 years, the human brain has continued to evolve. Two genes–microcephalin and ASPM–appear to play a role in determining the size of the human brain. They were first discovered in studies of microcephaly, a congenital disease in which people are born with smaller than average brains.

Brain size, however, isn’t necessarily correlated with intelligence. The genes may be useful in some tangential way, such as increased fertility or resistance to disease.

The discovery adds further weight to the view that human evolution is still a work in progress, since previous instances of recent genetic change have come to light in genes that defend against disease and confer the ability to digest milk in adulthood.

International Herald Tribune, September 9, 2005

ETA: More detailed discussions at Gene Expression and FuturePundit.

POSTED IN: General Genetics and Health

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