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Genetics and Health

Genes and Fractures in the Elderly

by Hsien Hsien Lei, PhD on September 15th, 2005

In both men and women, physiological changes that accompany aging, such as weaker sight, hearing, muscle strength, coordination, and reflexes, combined with fragile bones due to osteoporosis can result in debilitating injuries.

In a study of more than 6,000 elderly Swedish twins, more than half of the fractures experienced in this group resulted from osteoporosis. Genes appeared to account for less than 20 percent of the difference in overall age-adjusted fracture risk. Genetic factors had a stronger influence in the risk of first-time fracture in those younger than 70.

“We conclude that the genetic influence on susceptibility to fractures is dependent on type of fracture and age at fracture event,” the study authors wrote in the Sept. 12 issue of the Archives of Internal Medicine.

The National Institute on Aging has these and other tips for preventing falls and fractures:

  • Get a bone mineral density test.
  • Get regular exercise.
  • Check your vision and hearing regularly.
  • Find out about the possible side effects of medicines you take.
  • Limit alcohol intake.
  • Always stand up slowly after eating, lying down, or resting.
  • Don’t let your home get too cold or too hot…it can make you dizzy.
  • Use a cane, walking stick, or walker to help you feel steadier when you walk.
  • Hold the handrails when you use the stairs.

Forbes.com, September 13, 2005

POSTED IN: Genetics of Disease

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