Y Chromosome Genes and Blood Pressure
In a small study of 105 black boys and 156 white boys, researchers found that genes on the Y chromosome affect blood pressure starting at the age at which boys experience the biggest spurt in growth. The association between the HindIII genotype and blood pressure persisted even after puberty, especially in black males.
Compared to boys with the HindIII(+) gene variant, boys with the HindIII(-) gene variant had a 2.6 mm Hg higher systolic blood pressure and a 2.3 mm Hg higher diastolic pressure. Keep in mind, though, that lifestyle factors such as weight, diet, and exercise also influence blood pressure. These results are preliminary and show that it may be possible to use genes to determine who is at higher risk of hypertension.
“Even from a younger age, we have a way to track younger males and see who is going to be at a higher risk,” said lead researcher Fadi J. Charchar, a lecturer in cardiovascular science at the University of Glasgow. “This is going to be very important for preventive methods and treatment.”
To learn how to lower your blood pressure, see the NHLBI Guide to Lowering High Blood Pressure.
Forbes.com, September 22, 2005
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POSTED IN: Genetics of Disease
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