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Genetics and Health

Gene Increases Risk of Death, Heart Attack, or Stroke

by Hsien Hsien Lei, PhD on November 17th, 2005

Results from the International Verapamil SR-Trandolapril study (INVEST-GENES) show that hypertensive patients who carry the tryptophan version of the alpha-adducin gene have a 43 percent higher risk of death, heart attack or stroke. Up to 40 percent of the general population may carry at least one copy of the tryptophan variant.

Dr. Julie Johnson, director of the UF Center for Pharmacogenomics, said:

One of the goals of our research is to identify the genes that are related to patient-to-patient differences in response to medications. Personalizing drugs based on genetic makeup instead of taking a trial-and-error approach could lead to safer, more effective treatments for individual patients.

EurekAlert, November 17, 2005

POSTED IN: General Genetics and Health

1 opinion for Gene Increases Risk of Death, Heart Attack, or Stroke

  • rhonda
    Jan 8, 2008 at 7:21 pm

    Thanks for the notice. If you could include information, such as how one may test it they have this variation, it would be helpful.

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