Warfarin Sensitivity DNA Test
Kimball Genetics, Inc. has launched the Warfarin Sensitivity DNA Test for routine clinical use early next year. It tests for variations in the CYP2C9 and VKORC1 genes which play a role in determining a person’s sensitivity to warfarin via metabolism and anticoagulation processes, respectively. Warfarin (brand name Coumadin) prevents blood clots and is typically prescribed for patients who are experiencing irregular heartbeat or those who’ve had a heart attack or heart valve replace surgery.
The Warfarin Sensitivity DNA Test that Kimball offers informs the prescriber about the presence of genetic risk factors for overanticoagulation and should help achieve the correct maintenance dose faster. It is also likely to increase the safety and efficacy of warfarin treatment. The DNA test identifies patients who are sensitive to warfarin and who therefore: 1) require a lower dose to achieve a target INR, 2) may be at an increased risk for bleeding complications, and 3) without the DNA test, would require a longer period of time to achieve stable warfarin dosing.
I hear the bells of personalized medicine tolling once more.
Medical News Today, November 15, 2006
Technorati Tags: personalized medicine, warfarin, coumadin, genetics, genes, kimball, warfarin sensitivity dna test, dna, diseases, illness, health
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POSTED IN: General Genetics and Health, Genetic Testing
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7 opinions for Warfarin Sensitivity DNA Test
A Hearty Life » Warfarin Sensitivity DNA Test
Nov 15, 2006 at 11:51 pm
[…] If you’re a heart patient taking anticoagulant warfarin also known as Coumadin, you might be interested in learning more about the Warfarin Sensitivity DNA Test that will be available in 2007. Getting tested could help you calibrate the drug dosage that’s just right for you. […]
Genetics and Health » Genetics Forecast from Francis Collins
Nov 20, 2006 at 7:26 pm
[…] Popular use of direct-to-consumer DNA testing whether justified or not. […]
Science Surf
Nov 20, 2006 at 8:03 pm
Pharmacogenetic tests on the market…
……
A Hearty Life » Vice President Dick Cheney Has Deep Venous Thrombosis
Mar 6, 2007 at 12:19 am
[…] DVT’s are usually not serious and can be easily treated with anticoagulants warfarin and heparin. But warfarin dosage is notoriously difficult to calibrate and in late 2006, a genetic test was made available to determine a person’s metabolic and anticoagulation profile. […]
Yue Wang
Dec 20, 2007 at 9:07 pm
May I know what are the CPT codes for Warfarin Sensitivity DNA test please?
Thanks,
BILL MAXELL
Mar 16, 2008 at 6:12 pm
This sounds like something I need. My coumadin jumps up and down constantly even though I have been taking it for 5 years already. I t scares me. Also I need to know. Do canned greens have less vitamin K than fresh greens? How much is too much. I love my greens. Also is this test covered ny Keystone 65 health plan?
CARROL RUDGE
Mar 19, 2008 at 5:21 pm
Is the INR test available in the UK
Thankl you
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