30 Genes for Multiple Sclerosis and Other Autoimmune Diseases
A set of 30 genes, regulated by Foxp3, are believed to be involved in autoimmune disorders including multiple sclerosis. These gene variants cause regulatory T cells to go haywire thus leading the immune system to attack the body. Newsweek has an interview with Richard Young and Alexander Marson of MIT’s Whitehead Institute. Here’s an excerpt:
And these are the 30 genes, the ones that aren’t following the proper directions. So you think this dysfunction is the basis not just for one disorder, but a whole host of autoimmune diseases?
Marson: Yes, regulatory T cells appear to be key in preventing type 1 diabetes, lupus, multiple sclerosis, rheumatoid arthritis, and inflammatory bowel disease, as well as autoimmune thyroid disorders. Dysregulation of the genes controlling those cells could contribute to a wide range of autoimmune conditions.
Nature, January 21, 2007
Tags: t cells, treg cells, foxp3, genetics, genes, dna, autoimmune disease, multiple sclerosis, diseases, illness, health
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POSTED IN: Genetics of Disease
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1 opinion for 30 Genes for Multiple Sclerosis and Other Autoimmune Diseases
Czes Kulvis
May 9, 2008 at 7:09 am
If I understand correctly - the reason of my (as well as any other’s) Multiple Sclerosis or any other autoimmune disease are incorrect genes.
Is it correct?
If so, no person suffering from MS etc can do anything to improve their condition.
Not good.
Anyhow thanks for information
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