Genetics in the National Geographic Magazine
The February issue of the National Geographic Magazine has an amazing feature on the heart. The lead story by Jennifer Kahn discusses the genetics of heart disease in detail.
“Heart disease is not a one- or two-gene problem,” says Steven Ellis, a Cleveland Clinic cardiologist who oversees a 10,000-person genetic study known as GeneBank that collects DNA samples from patients who enter hospitals with atherosclerosis. Ellis, like most cardiac researchers, suspects that dozens of genes end up contributing to a predisposition: Some affect arterial integrity, others inflammation (which both causes and exacerbates arterial cracks), and still others the processing of lipids (the fats and cholesterol that turn into plaques). Of the several dozen genes, each may contribute just one percent to a person’s total risk—an amount that may be compounded, or offset, by outside factors like diet. As one doctor told me, any person’s heart attack risk is “50 percent genetic and 50 percent cheeseburger.”
Francis Collins is also featured in the Voices section of the magazine in an interview talking about the relationship between science and religion.
John Horgan: Free will is a very important concept to me, as it is to you. It’s the basis for our morality and search for meaning. Don’t you worry that science in general and genetics in particular—and your work as head of the Genome Project—are undermining belief in free will?
Francis Collins: You’re talking about genetic determinism, which implies that we are helpless marionettes being controlled by strings made of double helices. That is so far away from what we know scientifically! Heredity does have an influence not only over medical risks but also over certain behaviors and personality traits. But look at identical twins, who have exactly the same DNA but often don’t behave alike or think alike. They show the importance of learning and experience—and free will. I think we all, whether we are religious or not, recognize that free will is a reality. There are some fringe elements that say, “No, it’s all an illusion, we’re just pawns in some computer model.” But I don’t think that carries you very far.
Tags: genetics, genes, dna, francis collins, national geographic, heart, heart disease, diseases, illness, health, religion, science
Related Stories
POSTED IN: General Genetics and Health, Genetics of Disease
.gif)
0 opinions for Genetics in the National Geographic Magazine
No one has left a comment yet. You know what this means, right? You could be first!
Have an opinion? Leave a comment: