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Genetics and Health

Archive for the ‘BRCA’ Category

April 12th, 2008

Navigenics - the whole interview

G&H’s INTERVIEW WITH NAVIGENICS
Navigenics approached Genetics and Health for an interview. With so much written about similar genomics companies such as 23andme, Knome, deCODE genetics, I was intrigued to learn more about this company.  In particular, Navigenics appears to be the only company within this industry genre who provides a comprehensive wellness model – a […]

By Elaine -- 2 comments

April 9th, 2008

Navigenics #4 - “Low penetrance genes v high penetrance genes”

In this fourth in the series of articles originating from G&H’s exlusive interview with Navigenics’ Medical Director Dr Michael Nierenberg, we look at the whole issue of low penetrance versus high penetrance gene testing. 
SNPs are known as ‘low penetrance genes’ where it will only sometimes produce the symptom or trait with which it has been associated […]

By Elaine -- 0 comments

January 10th, 2008

Breast cancer risk varies amongst BRCA gene carriers

 
Breast awareness and regular checking are important in early detection of breast cancer
Further to my articles on the BRCA breast cancer genes, an American and Danish study has found the risk of developing cancer amongst carriers of the BRCA1 and 2 breast cancer gene mutations varies greatly.  The risk of breast cancer in BRCA1 and […]

By Elaine -- 0 comments

December 10th, 2007

50% BRCA 1 genes have PTEN mutations

Nature Genetics has published a report by scientists in US and Sweden who have discovered how a variant of the BRCA 1 gene helps breast cancer to grow by knocking out a tumor suppressor gene called PTEN.
The link between BRCA 1 and breast cancer was established 10 years ago but questions have been asked as to […]

By Elaine -- 0 comments

October 31st, 2007

Happy Birthday BRCA2!

It’s the last day of Breast Awareness month, so I thought this post would be quite apt!
This year sees the tenth anniversary of the discovery of breast cancer gene BRCA2!
According to estimates of lifetime risk, about 13.2% of women will develop breast cancer, compared with estimates of 36% to 85% with an altered BRCA2 gene.  […]

By Elaine -- 2 comments

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