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I’ve known UK diagnostics company Lab-21 for some years now. My previous company Opaldia and Lab-21 effectively ‘grew up’ together.
Amgen Limited UK and Lab21 have announced their partnership to introduce a new genetic therapy test for advanced bowel cancer treatment. Under the terms of the agreement, Lab21 will provide a screening test to indicate which patients are likely […]
Prostate cancer
(Picture courtesy of BBC)
UK scientists have found seven new sites in the human genome that are linked to men’s risk of developing prostate cancer. Dr Ros Eales and Prof Doug Easton from The Institute of Cancer Research and University of Cambridge respectively, found one gene called MSMB which could possibly be used in screening […]
The EU funded GEN2PHEN project plans to internationally orchestrate the electronic gathering and use of data that show how gene sequences (’genotypes’) contribute to individual differences in disease, drug response, and other characteristics (’phenotypes’). These relationships (usually in the form of “genotype-phenotype” information stored in scattered databases) are deemed to become essential for future prognosis, […]
The U.S. Food and Drug Administration (FDA) has approved a test that helps in assessing the risk of tumor recurrence and long-term survival for patients with relatively high-risk breast cancer. The TOP2A FISH pharmDx is the first approved device to test for the TOP2A (topoisomerase 2 alpha) gene in cancer patients.
The TOP2A gene plays a […]
(Stylized rendering of a cross section of the AIDS virus)
New HIV infections are averaging around 2.5m per annum worldwide, and growing.
Most people infected with HIV produce antibodies against the virus within several weeks following infection, these antibodies rarely prevent the infection from progressing to symptomatic AIDS.
However a recent study involving a group of women from […]
Being able to sequence a human genome for $1,000 or less (which is the price most insurance companies are willing to pay) could open a new era in personal medicine, making it possible to precisely diagnose the cause of many diseases and tailor drugs and treatment procedures to the genetic make-up of an individual.
Professor Aleksei […]
There is increasing evidence that there is a genetic link between schizophrenia and cancer, providing a surprising possible scientific explanation for lower rates of cancer among patients with schizophrenia - despite having poor diets and high rates of smoking - and their parents.
It would seem that many of the genes associated with schizophrenia are the same […]
Here’s an interesting article from the BBC website.
Scientists believe they have located a new brain area essential for good memory - the “irrelevance filter”.
People who are good at remembering things, even with distractions, have more activity in the basal ganglia on brain scans, the Swedish team found.
The work in Nature Neuroscience could help explain why […]
Nature Genetics has published a report by scientists in US and Sweden who have discovered how a variant of the BRCA 1 gene helps breast cancer to grow by knocking out a tumor suppressor gene called PTEN.
The link between BRCA 1 and breast cancer was established 10 years ago but questions have been asked as to […]
Embryonic stem cells are derived from human embryos. They are valued as they are shown to be ‘pluripotent’ - having the capability to become any of the 220 types of cell in the human body. They have the potential to generate new heart, liver, brain, muscle and bone tissue to replace diseased or damaged tissue in people […]
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