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P52 gene, arrows show locations of common mutations
(Image courtesy www.bioinf.org)
Following on from my last article on using gene therapy for increasing survival in head and neck cancer, Professor Jack Roth, M.D., professor in M. D. Anderson’s Department of Thoracic & Cardiovascular Surgery and colleagues are now focusing on ways to deliver p53 and other tumor-suppressing genes […]
Thank you to Jennifer Texada at MD Anderson for bringing this great cancer treatment discovery to my attention….
(Image courtesy Introgen Therapeutics)
A gene therapy invented at The University of Texas M. D. Anderson Cancer Center is the first to succeed in a U.S. phase III clinical trial for cancer. Introgen Therapeutics, Inc a spin out from MD […]
Maxi-K gene therapy may be a safe and effective future option for men whose erectile dysfunction (ED) is not treatable with oral therapy. This therapy is not yet available commercially but shows immense promise for the future.
Maxi-K therapy is a unique, locally administrated gene-transfer technology to treat erectile dysfunction (ED). The safety and the restorative […]
Scientists from Newcastle University, UK led by Professor Patrick Chinnery, have created an embryo with three separate parents. The team believe the technique could help to eradicate a whole class of hereditary diseases, including some forms of epilepsy and ensure women with genetic defects do not pass the diseases on to their children.
Ten severely deformed embryos, left […]
New research has shown evidence that genes have the ability to recognize similarities in each other from a distance, without any proteins or other biological molecules aiding the process. This discovery could explain how similar genes find each other and group together in order to perform key processes involved in the evolution of species.
According to […]
Micrograph images of synthetic Mycoplasma genitalium
J Craig Venter and his team at the J Craig Venter Institute Rockville, Md. Venter continue to expand our horizons of what constitutes life. They have built, from scratch, a synthetic chromosome containing all the genetic material needed to produce a primitive bacterium - this is considered a giant step toward the creation […]
The EU funded GEN2PHEN project plans to internationally orchestrate the electronic gathering and use of data that show how gene sequences (’genotypes’) contribute to individual differences in disease, drug response, and other characteristics (’phenotypes’). These relationships (usually in the form of “genotype-phenotype” information stored in scattered databases) are deemed to become essential for future prognosis, […]
Early embryos yield stem cells,(photo courtesy of BBC news www.bbc.co.uk/news)
The Uk’s fertility regulator Human Fertilisation and Embryology Authority (HFEA) has given the green light to two teams of scientists for the creation of hybrid human-animal embryos.
Scientists, research institutions and patient groups have challenged the UK government for much of the last year: the Department of Health wanted […]
In evolutionary terms bats and mice are separated by millions of years.
An MD Anderson team led by Dr Richard Behringer successfully switched the mouse Prx1 gene regulatory element with the Prx1 gene regulatory region from a bat - the resulting transgenic mice displayed abnormally long forelimbs.
While forelimb length is just one of several key […]
Being able to sequence a human genome for $1,000 or less (which is the price most insurance companies are willing to pay) could open a new era in personal medicine, making it possible to precisely diagnose the cause of many diseases and tailor drugs and treatment procedures to the genetic make-up of an individual.
Professor Aleksei […]
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