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Genetics and Health

June 8th, 2008

Elite athletes who died of enlarged hearts may have a genetic mutation

Enlarged hearts are found often, but not exclusively, in those who are obese, have diabetes or high blood pressure. People with none of these underlying problems can be affected, as can elite athletes.  For example, a post-mortem diagnosed the problem in Cameroon football midfielder Marc-Vivien Foe, who died in 2003 after collapsing during an international match […]

By Elaine -- 0 comments

May 5th, 2008

Weight gain, diabetes, expanding waist line and a gene sequence

 
Scientists from Imperial College London and other international institutions have discovered a gene sequence that is associated with a 2cm expansion in waist circumference, a 2kg gain in weight, and a tendency to become resistant to insulin, which can lead to type 2 diabetes. The sequence is found in 50% of the UK population.
The study shows that the […]

By Elaine -- 2 comments

April 12th, 2008

Navigenics - the whole interview

G&H’s INTERVIEW WITH NAVIGENICS
Navigenics approached Genetics and Health for an interview. With so much written about similar genomics companies such as 23andme, Knome, deCODE genetics, I was intrigued to learn more about this company.  In particular, Navigenics appears to be the only company within this industry genre who provides a comprehensive wellness model – a […]

By Elaine -- 3 comments

March 19th, 2008

Entire gene networks involved in susceptibility to obesity

 
Many gene studies focus on WHICH genes cause a person’s risk of developing a disease (forward genetics) but few focus on HOW those genes can lead to disease.  Researchers at Merck and Co, deCODE genetics and academic centres in the US and France have focused on the latter and shed light on the complexity of common disease causes where […]

By Elaine -- 1 comment

February 16th, 2008

Genetic adaptations to surviving a cold climate linked to diabetes, obesity and heart disease

 
Our early human ancestors originated from a hot, humid climate where natural selection focused on dispersing heat.  As humans migrated to colder climates there would have been evolutionary pressure to adapt to their new settings by boosting the processes that produce and retain heat.
Genes involved in energy metabolism are therefore likely to be central to heat and cold […]

By Elaine -- 0 comments

April 16th, 2007

DNA Direct and deCODE Offering TCF7L2 Genetic Testing for Type 2 Diabetes

Knowing more about your risk of type 2 diabetes is just a keyboard click away at DNA Direct. Together with deCODE diagnostics, DNA Direct is now offering deCODE T2, a genetic test that examines the presence of the “T” allele of SNP rs7903146, located within the transcription factor 7-like 2 (TCF7L2) gene. Almost twice as […]

By Hsien Hsien Lei, PhD -- 34 comments

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